Recent Advancement in Prodrugs e-bog

Recent Advancement in ProdrugsDrugs used as medicines have many limitations like low chemical stability, aqueous solubility, or oral absorption/bioavailability, rapid presystemic metabolism, toxicity, inadequate site specificity, or poor patient acceptance/compliance (unwanted adverse effects, unacceptable taste or odor, irritation or pain). Prodrugs design is an approach to overcome these limitations.Key featuresCovers recent advancements in development of prodrugsPresents balanced synthesis and applications of prodrug chemistryDiscusses broad spectrum of prodrug categories and outlines industrial applicationsReviews prodrugs in cancer nanomedicine, its therapy and treatmentElucidates mathematical models to study the kinetics of prodrugsThis book covers recent advances in the design of prodrugs. It contains all the significant recent examples of prodrug chemistry developments and will aid academics and researchers seeking to generate new projects in the field.