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Dose Finding by the Continual Reassessment Method e-bog
436,85 DKK
(inkl. moms 546,06 DKK)
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinical settings. The book includes examples of real clinical trials data to illustrate the calibration techniques and shows how R can be used to carry ...
E-bog
436,85 DKK
Forlag
Chapman and Hall/CRC
Udgivet
29 marts 2011
Længde
200 sider
Genrer
MBNS
Sprog
English
Format
pdf
Beskyttelse
LCP
ISBN
9781420091526
This book presents the continual reassessment method (CRM) as a tool for dose-finding studies. With a focus on the implementation and practice of the CRM and its variations, it explains how the CRM may be calibrated and extended to suit common clinical settings. The book includes examples of real clinical trials data to illustrate the calibration techniques and shows how R can be used to carry out the techniques. It reviews the literature, related methodology, and theoretical properties of the CRM. It also explores alternatives for situations where the CRM fails.