IgM and Its Receptors and Binding Proteins (e-bog) af -
Burrows, Peter D. (redaktør)

IgM and Its Receptors and Binding Proteins e-bog

1021,49 DKK (inkl. moms 1276,86 DKK)
This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three...
E-bog 1021,49 DKK
Forfattere Burrows, Peter D. (redaktør)
Forlag Springer
Udgivet 24 oktober 2017
Genrer Diseases and disorders
Sprog English
Format epub
Beskyttelse LCP
ISBN 9783319645261
This volume reviews the current state of research on the IgM antibody and its multiple receptors and binding proteins. Interactions of the IgM ligands with these molecules are important for protection against infections as a first line of defense, as well as for regulation of immune responses to pathogens and self-antigens. The book includes up-to-date information on: (i) the phylogeny of three IgM-binding receptors [polymeric Ig receptor (pIgR), Fc receptor for both IgA and IgM (Fca/uR), and Fc receptor for IgM only (FcuR)]; (ii) the lymphocyte-restricted distribution and unique ligand-binding activity of FcuR; (iii) the definition and potential function of Fc receptor-like molecule A (FCRLA) as a resident endoplasmic reticulum protein that binds IgM, but also IgG and IgA; (iv) IgM antibody-mediated enhancement of humoral immune responses, highlighting the importance of complement and its receptors, (v) the numerous important roles of IgM natural antibodies in regulation of inflammation. It is an invaluable resource for researchers and clinicians alike.