Drug Metabolism and Transport (e-bog) af -
Lash, Lawrence H. (redaktør)

Drug Metabolism and Transport e-bog

1240,73 DKK (inkl. moms 1550,91 DKK)
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuroni...
E-bog 1240,73 DKK
Forfattere Lash, Lawrence H. (redaktør)
Forlag Humana
Udgivet 6 februar 2008
Genrer MQP
Sprog English
Format pdf
Beskyttelse LCP
ISBN 9781592598328
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.