Multifaceted Role of IL-1 in Cancer and Inflammation e-bog

Multifaceted Role of IL-1 in Cancer and Inflammation summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. The book presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment and covers topics on the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors. This is a valuable source for cancer researchers, clinicians and other members of the biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies. Presents a summary in the beginning of each chapter to help readers to find the needed information and understand the content easily Encompasses detailed schematic diagrams and illustrations throughout the content to explain the complex immune mechanisms discussed Discusses future perspectives in all chapters to motivate researchers to work on emerging problems Includes contributions from internationally renown experts sharing their experiences on clinics and research