Histaminergic and Non-Histaminergic Itch: From Channels to Behavior e-bog
802,25 DKK
(inkl. moms 1002,81 DKK)
Itch (pruritus) is an unpleasant skin sensation that compels a person to scratch the affected area. The pathological consequences of itching affect the quality of life just as much as pain. Chronic pruritus conditions such as atopic dermatitis, allergic contact dermatitis, or psoriasis pose a significant socioeconomic burden. This book provides an original account of behavioral, cellular, and m...
E-bog
802,25 DKK
Forlag
Nova Medicine and Health
Udgivet
11 juli 2023
Længde
153 sider
Genrer
Popular medicine and health
Sprog
English
Format
pdf
Beskyttelse
LCP
ISBN
9798886978827
Itch (pruritus) is an unpleasant skin sensation that compels a person to scratch the affected area. The pathological consequences of itching affect the quality of life just as much as pain. Chronic pruritus conditions such as atopic dermatitis, allergic contact dermatitis, or psoriasis pose a significant socioeconomic burden. This book provides an original account of behavioral, cellular, and molecular aspects of itch in experimental rodents and human subjects. It concentrates on the role of different cellular membrane ion channels functioning in itch states and spinal and cortical pathways which mediate the neural cascade of itch-signaling. The book shows that ion channels are promising targets for developing a new group of antipruritic drugs at the periphery and central levels for therapeutic intervention.